Ref 25
Live It
Hype watch
Strong convictions, loosely held - Attia revises his own playbook
12th October 2026
In AMA #90, Peter Attia looks back over 400 episodes and publicly updates positions he once held firmly: he no longer takes metformin for longevity, his confidence in rapamycin has cooled, and his views on extended fasting, keto, whole-body MRI and heavy barbell training have all become more conditional. The through-line is method, not dogma - durable principles and sustainable practice over marginal optimisation.
Key takeaways:
- Metformin: no longer viewed as protective for metabolically healthy people; rapamycin: strong animal data, unresolved human dosing
- Screening: whole-body MRI quality questioned in favour of more targeted detection; liquid biopsy still early, early-stage detection is what counts
- Training: less dogma on Zone 2 splits and heavy squats/deadlifts; benefit weighed against injury risk and time available
Why it matters - This is the evidence-over-hype lens applied by one of the field’s most cited voices to his own past advice - a useful model for how readers should hold every claim in this library.